3-FLUORO-4-METHOXYBENZOYL CHLORIDE

3-FLUORO-4-METHOXYBENZOYL CHLORIDE - Names and Identifiers

Name	3-Fluoro-4-methoxybenzoyl chloride
Synonyms	SKL1263 3-Fluoro-4-methoxybenzoyl chloride 3-fluoro-4-methoxylbenzoyl choride 4-(Chlorocarbonyl)-2-fluoroanisole 3-FLUORO-4-METHOXYBENZOYL CHLORIDE Benzoyl chloride, 3-fluoro-4-methoxy- 4-(Chlorocarbonyl)-2-fluoroanisole, 4-(Chloroformyl)-2-fluoroanisole
CAS	3907-15-1
InChI	InChI=1/C8H6ClFO2/c1-12-7-3-2-5(8(9)11)4-6(7)10/h2-4H,1H3

3-FLUORO-4-METHOXYBENZOYL CHLORIDE - Physico-chemical Properties

Molecular Formula	C8H6ClFO2
Molar Mass	188.58
Density	1.309±0.06 g/cm3(Predicted)
Melting Point	68-71°C
Boling Point	135 °C(Press: 11 Torr)
Flash Point	120.7°C
Vapor Presure	0.0082mmHg at 25°C
Storage Condition	Room Temprature
Sensitive	Moisture Sensitive
Refractive Index	1.511
MDL	MFCD03428589

3-FLUORO-4-METHOXYBENZOYL CHLORIDE - Risk and Safety

Risk Codes	22 - Harmful if swallowed
UN IDs	UN3261
Hazard Note	Corrosive
Hazard Class	8
Packing Group	II

3-FLUORO-4-METHOXYBENZOYL CHLORIDE - Introduction

chloride is an organic compound whose chemical formula is C8H6ClFO2.

Nature:
-Appearance: Colorless to light yellow liquid
-Melting point: 22-25 ℃
-Boiling point: 148-151 ℃
-Density: 1.35g/cm³
-Good solubility in non-polar solvents, such as ether and dichloromethane

Use:
-chloride is an organic synthesis intermediate commonly used in the synthesis of pesticides, pharmaceuticals and other organic compounds.
-It can be used as a derivative of substituted benzoyl chloride for the synthesis of target compounds with specific physical and chemical properties.

Preparation Method:
The chloride is usually synthesized by the following methods:
1. reaction raw materials: 3-fluoro-4-methoxybenzoic acid and Thionyl chloride (sulfuryl chloride).
2. 3-fluoro-4-methoxybenzoic acid and an excess amount of sulfuryl chloride are put into a reaction vessel, and the reaction is heated, usually under an inert atmosphere.
3. After the reaction is completed, the solid impurities are filtered and distilled to obtain the target product-chloride.

Safety Information:
-chloride is an organic synthetic compound that may cause irritation to the skin, eyes and respiratory tract, so use personal protective equipment such as gloves, goggles and respiratory protection.
-During storage and handling, avoid contact with oxidants, strong acids or strong bases.
-If ingested or touched by mistake, seek medical attention immediately and show the compound's safety data sheet to the doctor.

Last Update：2024-04-09 20:49:11